Professor Dr. Mohammad Abdur Rashid
Dean, Faculty of Pharmacy
University of Dhaka
Research Fields
Dhaka University

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Research Experience

1)  Scientist II- SAIC-Frederick, NCI-Frederick, Frederick, MD 21702 from May 5, 2000 to November 29, 2001.  I was involved in the isolation & characterization of anticancer compounds from marine organisms.

2)   Visiting Scientist- SAIC-Frederick, NCI-Frederick, Frederick, MD 21702 from December 9, 1997 to May 5, 2000, where I was involved in the isolation & characterization of  anticancer and HIV-inhibitory lead compounds, with special emphasis to peptides from aqueous marine extracts.

3)  Post Doctoral- I carried out a two year of research (from April 1993 to March 1995) at the U.S. National Cancer Institute which was supervised by Dr. Kirk R. Gustafson. As a member of the research group headed by Dr. John H. Cardellina II, I successfully completed more than a dozen of projects dealing with the anti-cancer and HIV-inhibitory activities of the aqueous/ organic extracts of plants, marine and microbial organisms. A variety of compounds such as alkaloids, antibiotics, polyacetylenes, saponins, pterocarpans, lignans and peptides were obtained as active constituents.

4)  Doctoral research- During my Ph.D. research at the University of Strathclyde, under the supervision of Prof. Peter G. Waterman and Dr. Alexander I. Gray, I submitted a thesis entitled “Phytochemical and Chemosystematic Studies in Eristemoninae (Rutaceae).” This thesis describes the isolation and structure elucidation of a total of 93 compounds, including 34 novel ones from 11 Australian plant species and their uses as chemotaxonomic markers.

5)   Carried out a research project in partial fulfillment of the requirement for the degree of Master of Pharmacy, University of Dhaka and submitted a dissertation entitled “Antihypertensive Principle from Moringa oleifera.”

6)  Supervised/ co-supervised various research projects of the students approaching towards the degrees of M. Pharm./M.Sc./M. Phil./Ph.D. at the University of Dhaka and the Institute of Post Graduate Medicine & Research  (IPGMR), Dhaka-1000, Bangladesh.

 
Instrumentation Expertise
HPLC, UV, IR/ FTIR, 500 MHz Varian NMR, etc. I am capable to record the routine 1H- and 13C- NMR spectra as well as to run the modern 2D experiments such as 1H-1H COSY, DQF-COSY, NOESY, ROESY, TOCSY, HSQC, HMBC and HSQC-TOCSY, etc., which are considered as the back bone of Natural Products Chemistry.
 
Research Interest

Isolation and characterization of bio-active compounds from medicinal plants, microbes and      marine animals.

Application of modern NMR techniques to structure elucidation of organic molecules, with special emphasis to marine peptides and macrolides.

In addition to my main stream research, my research interests will be extended to other aspects of natural products chemistry: evaluation of traditional medicinal plants, chemical taxonomy of higher plants, insect control agents from plants, etc.